Antonio Conte’s side travel to Stamford Bridge on Wednesday, having already had three matches postponed in December, when a COVID-19 outbreak impacted nine members of their first-team squad.
Speaking to the media ahead of the Chelsea match, Conte said: “We are checking a couple of situations about COVID concerning players and we’ll see.
“We are not sure 100 per cent whether they are going to miss the game.
“We have to check and also during the day if there are new positives or not. We are checking a couple of situations and then tomorrow will see the players that are available to play the game against Chelsea.”
Conte gave no indication that Tottenham would appeal for the match to be postponed, however.
“We are living with this situation, not only Tottenham but I think all the clubs.
“We have to be ready to always find the right solution and the best solution for the team. It’s not simple for every coach to change the plan, the plan that you have in your mind, especially when you play many games in a short time.
“In your mind you make a plan, sometimes you arrive, players (test) positive and you have to totally change your plan. It’s not easy, not only for me but all the managers.”
After travelling to Chelsea, Spurs face League One Morecambe in the third round of the FA Cup on Sunday.